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Melatonin has been shown to have anti-inflammatory effects, amongst a number of activities. Melatonin reduces tissue damage throughout inflammatory reactions by a variety of means. Thus melatonin, by virtue of its capability to straight feed on toxic free radicals, decreases macromolecular damage in all body organs. The free radicals and responsive oxygen and nitrogen types known to be fed on by melatonin consist of the very poisonous hydroxyl radical, peroxynitrite anion, as well as hypochlorous acid, to name a few. These agents all contribute to the inflammatory feedback and also linked cells destruction. Additionally, melatonin has other means to lower the damage arising from swelling.
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